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Antiocardiolipin antibodies(aCL)are a risk factor for cerebral ischemia.In migraine,the association is controversial,with widely varying results in different small series.The controversy in party may be due to the inherent difficulty in distinguishing the transient focal neurologic events(TFNE)of migraine from TIA.Findings on imaging consistent with cerebral ischemia were more frequently in aCL-positive persons.The short-term risk of stroke was uniformly low.In young persons,aCL is not associated with migraine or with TFNE,although diabetes mellitus,negative family history of stroke,and brief duration of symptoms(including diplopia)may predict immunoreactivity.Imaging studies suggest an ischemic etiology of TFNE in this cohort. |
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